Effect of oxygen levels on the human embryo development in embryo culture

Šogorić, Sonja (2012) Effect of oxygen levels on the human embryo development in embryo culture. Diploma thesis, Faculty of Science > Department of Biology.

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Abstract

Considering the number of children conceived through in vitro fertilization (IVF), assisted reproduction is a very important choice of treatment because it increases the probability of pregnancy in couples with infertility problems. It is assumed that oxygen, along with the composition of the media culture, is a key factor in development of embryos in vitro, becouse it causes the formation of reactive oxygen species, which are considered the main factors responsible for the unsatisfactory results of IVF. The goal of the research was to compare the structure of human embryos from fertilization to embryo transfer into the uterus during in vitro cultivation in conditions with oxygen levels of 21% and 5% with the degree of clinical pregnancies. Embryos cultured in incubators with 5% level of oxygen are more likely to reach the blastocyst stage and resulted in a larger number of pregnancies. Cultivation of embryos in incubators with 5% oxygen contributes to their overall better development.

Item Type: Thesis (Diploma thesis)
Keywords: in vitro fertilization, 5% oxygen, embryo development, blastocysts
Supervisor: Benković, Vesna
Date: 2012
Subjects: NATURAL SCIENCES > Biology
Divisions: Faculty of Science > Department of Biology
Depositing User: Grozdana Sirotic
Date Deposited: 06 Jun 2014 08:07
Last Modified: 06 Jun 2014 08:07
URI: http://digre.pmf.unizg.hr/id/eprint/2280

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