Impact of retinoic acid on embryonic development of mammals

Žalac, Sanja (2009) Impact of retinoic acid on embryonic development of mammals. Bachelor's thesis, Faculty of Science > Department of Biology.

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Abstract

Normal morphogenesis of vertebrate embryos is severely affected by externally doses of retinoic acid. Typically it leads to craniofacial abnormalities and heart defects and to limb deformities. Limbs in development are sensitive to deficiency and excess of RA. Genetic and biochemical manipulations indicate that retinoids are crucial for vertebate limb development at two stages, in early organogenesis for forelimb bud initiation, and later in mid-organogenesis, for proper limb outgrowth.

Item Type: Thesis (Bachelor's thesis)
Supervisor: Lacković Venturin, Gordana
Date: 2009
Number of Pages: 15
Subjects: NATURAL SCIENCES > Biology
Divisions: Faculty of Science > Department of Biology
Depositing User: Silvana Šehić
Date Deposited: 03 Oct 2014 08:39
Last Modified: 03 Oct 2014 08:39
URI: http://digre.pmf.unizg.hr/id/eprint/2911

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