Comparison of 1D and 3D protein alignment

Zagorščak, Maja (2009) Comparison of 1D and 3D protein alignment. Bachelor's thesis, Faculty of Science > Department of Biology.

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Abstract

This work is concerned with a comparison between structural and sequence alignment. It is well known that protein structures evolve more slowly than sequences, so detecting the “right” (i.e. structural) alignment from the sequence information only becomes increasingly difficult when dealing with distant homologues. It is shown that Miyazaw’s algorithm for sequence alignment performs this task more accurately than standard methods, such as Needleman-Wunsch, Smith-Waterman or BLAST.

Item Type: Thesis (Bachelor's thesis)
Supervisor: Goldstein, Pavle
Date: 2009
Number of Pages: 14
Subjects: NATURAL SCIENCES > Biology
Divisions: Faculty of Science > Department of Biology
Depositing User: Silvana Šehić
Date Deposited: 03 Oct 2014 08:54
Last Modified: 03 Oct 2014 08:54
URI: http://digre.pmf.unizg.hr/id/eprint/2913

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