Efficient recombination between diverged sequences: the role of λ Red protein

Rožić, Sara (2010) Efficient recombination between diverged sequences: the role of λ Red protein. Bachelor's thesis, Faculty of Science > Department of Biology.

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Abstract

Bacteriophages are bacterial viruses that inhabit even the remotest corners of our planet. The classification of these organisms into groups has always been very difficult and still poses a problem to many scientists and researchers. Temperate bacteriophages show a strong genomic mosaicism, and it is therefore impossible to determine their evolution. This study attempted to decipher whether the fact that Red proteins promote homologous recombination between diverged sequences affects genomic mosaicism of temperate bacteriophages, with emphasis on phage λ. Scientists have come up with a very interesting discovery: many lambdoid phages (temperate) have recombinases originating from the same family as recombinase Redβ, and virulent phages possess recombinases similar to the bacterial protein RecA. Virulent phages do not show mosaicism of their genome, which is further evidence that the bacteriophage λ Red system could have an impact on the creation of genomic mosaicism, and the evolution of temperate bacteriophages.

Item Type: Thesis (Bachelor's thesis)
Supervisor: Ivančić Baće, Ivana
Date: 2010
Number of Pages: 16
Subjects: NATURAL SCIENCES > Biology
Divisions: Faculty of Science > Department of Biology
Depositing User: Silvana Šehić
Date Deposited: 03 Oct 2014 09:32
Last Modified: 03 Oct 2014 09:32
URI: http://digre.pmf.unizg.hr/id/eprint/2916

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