Disorders in animal development caused by endocrine disruptive chemicals

Nanić, Lucia (2010) Disorders in animal development caused by endocrine disruptive chemicals. Bachelor's thesis, Faculty of Science > Department of Biology.

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An endocrine disruptor (EDC) is defined as an exogenous chemical substance or mixture that alters the structure or function of the endocrine system and causes adverse effects at the level of the organism, its progeny, and populations of organisms. Compounds with hormone-like activity can disrupt endocrine signaling pathways that play important roles during perinatal differentiation and result in alterations that are not apparent until later in life. Some of these compounds, such as oral contraceptives and a subset of pesticides, were specifically developed to target the endocrine system but the vast majority of these chemicals were neither designed nor intended to, especially in mammals. Some, such as DDT, were developed to kill mosquitoes and other pests that spread serious and in some cases life threatening human diseases such as malaria. Others were devised as flame retardants, to kill weeds, or to make plastics harder, clearer, and more resistant to heat stress (bisphenol A) or more pliable (the phthalates). Compounds produced in nature rather than by humans, such as the phytoestrogens (genistein), also fit this definition. Evidence implicates developmental exposure to environmental hormone-mimics with a growing list of health problems.

Item Type: Thesis (Bachelor's thesis)
Supervisor: Lacković Venturin, Gordana
Date: 2010
Number of Pages: 16
Subjects: NATURAL SCIENCES > Biology
Divisions: Faculty of Science > Department of Biology
Depositing User: Silvana Šehić
Date Deposited: 06 Oct 2014 10:03
Last Modified: 16 Feb 2016 14:05
URI: http://digre.pmf.unizg.hr/id/eprint/2936

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