The use of snake venom toxins in medicine

Mavrović, Martina (2010) The use of snake venom toxins in medicine. Bachelor's thesis, Faculty of Science > Department of Biology.

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Abstract

Snakes have started to diverge from the reptiles in Cretaceus (a geologic era of the Mesosoic which lasted form 136 million years ago untill 65 million years ago). They have developed the possibility of producing venom in Miocene (a geologic era of the Neogene, which lasted from 23.03 million years ago untill 5.33 million years ago). One hundred years ago it was proved possible to immunise an animal against snake venom, and make it resistant to the venom. With that event started the era of modern serotherapy, as well as other medicinal uses of snake venom toxins. Numerous drugs have already been synthetised based on toxins from snake venom, and numerous are still under research. Toxins are of interest in drug design because they provide a three-dimensional templade for the creation of small molecules which can mimic the effects of the toxin. The isolation and study of snake venom components has paved the way for a deeper understanding of the pathophisiology of envenomings, as well as opened a possibility to improve therapeutic modalities.

Item Type: Thesis (Bachelor's thesis)
Supervisor: Tadić, Zoran
Date: 2010
Number of Pages: 14
Subjects: NATURAL SCIENCES > Biology
Divisions: Faculty of Science > Department of Biology
Depositing User: Silvana Šehić
Date Deposited: 06 Oct 2014 10:59
Last Modified: 06 Oct 2014 10:59
URI: http://digre.pmf.unizg.hr/id/eprint/2944

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