Rabies biology

Randi, Dania (2011) Rabies biology. Bachelor's thesis, Faculty of Science > Department of Biology.

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Abstract

Rabies is a viral disease that causes acute encephalytis. It exists in urban and sylvatic form, and is transferred among mammals, most commonly by bite. Rabies virus is a bulletshaped RNA virus belonging to the genus Lyssavirus in the Rhabdoviridae family. It is neurotropic and travels retrogradely from axon endings to central nervous system. Disease development consists of prodromal, excitation and paralytic phase. Once the clinical symptoms develop, death is inevitable. The rabies problem is handled by prevention (vaccination of animals and people in high-risk groups) and post-exposition prophylaxis immediately after the exposure to pathogen. Most successful combination of vaccination is consisted of human anti-rabies immunoglobulin and viral particles isolated from human-cell cultures. Rabies presumably originated from Europe, and today is present on every continent except Australia.

Item Type: Thesis (Bachelor's thesis)
Supervisor: Tadić, Zoran
Date: 2011
Number of Pages: 14
Subjects: NATURAL SCIENCES > Biology
Divisions: Faculty of Science > Department of Biology
Depositing User: Silvana Šehić
Date Deposited: 07 Oct 2014 08:32
Last Modified: 07 Oct 2014 08:32
URI: http://digre.pmf.unizg.hr/id/eprint/2957

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