Probiotics – myth or reality?

Slović, Anamarija (2011) Probiotics – myth or reality?. Bachelor's thesis, Faculty of Science > Department of Biology.

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Abstract

A notion that not all bacteria are necessarily pathogenic; that, in fact, some of them carry numerous positive effects on human health led to forming the term probiotic. For a bacteria strain to be labeled probiotic, it must meet certain requirements, as well as have its positive effects correctly determined. For probiotics to fulfill their function they need to survive the gastrointestinal tract and arrive at the colon in sufficient numbers to affect the bacterial ecology and metabolism in that area. Relevant factors when traversing the tract include: stomach acid and bile acid resistance, ability to adhere to colon’s epithelial cells, modulation of host’s immunity response and probiotic’s antimicrobial activity. Potential human health benefits include modulation of mucosal immunity response, prevention and treatment of certain inflammatory bowel disorders, provided by probiotics labeled immunobiotics. Other than mucosal immunity response modulation, probiotics can directly affect the colon’s microflora by antimicrobial activity. Some do so by secreting nonspecific antimicrobial substances, such as short-chain fatty acids or hydrogen peroxide, while others produce toxins with very narrow killing ranges, such as bacteriocins.

Item Type: Thesis (Bachelor's thesis)
Supervisor: Šeruga Musić, Martina
Date: 2011
Number of Pages: 18
Subjects: NATURAL SCIENCES > Biology
Divisions: Faculty of Science > Department of Biology
Depositing User: Silvana Šehić
Date Deposited: 07 Oct 2014 10:29
Last Modified: 07 Oct 2014 10:29
URI: http://digre.pmf.unizg.hr/id/eprint/2966

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