Free radicals and antioxidants in normal physiological functions and human diseases

Postić, Sandra (2012) Free radicals and antioxidants in normal physiological functions and human diseases. Bachelor's thesis, Faculty of Science > Department of Biology.

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Abstract

Free radicals can be defined as molecules or parts of molecules that contain unpaired electrons in atomic orbitals. ROS are the most important types of free radicals generated within living beings. ROS i RNS are known for their dual role in the cell. One of the roles of free radicals is that they cause oxidative stress. Organisms have developed various defense mechanisms against oxidative stress. One of them is by using oxidative stress enzymes. Free radicals participate in many normal physiological processes such as: redox regulated production of NO, ROS production by phagocytic NAD(P)H oxidase, ROS production by NAD(P)H oxidases in nonphagocytic cells, ROS production as a sensor for changesof oxygen concentration, redox regulation of cell adhesion, redox regulation of immune responses and ROS-induced apoptosis. Oxidative stress has been found in various diseases such as cardiovascular disease, cancer, neurological disorders, diabetes…

Item Type: Thesis (Bachelor's thesis)
Supervisor: Oršolić, Nada
Date: 2012
Number of Pages: 17
Subjects: NATURAL SCIENCES > Biology
Divisions: Faculty of Science > Department of Biology
Depositing User: Silvana Šehić
Date Deposited: 13 Oct 2014 09:25
Last Modified: 13 Oct 2014 09:25
URI: http://digre.pmf.unizg.hr/id/eprint/3011

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