Embryonic stem cells

Bačić, Mateja (2012) Embryonic stem cells. Bachelor's thesis, Faculty of Science > Department of Biology.

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Embryonic stem cells differ from the other cells in a body by two main characteristics: the ability of self-renewal and pluripotency, the ability to develope any type of the cell from an undiferentiated state. Their origin, as opposed to adult stem cells, is very well researched. They originate from the inner cell mass of the embryo stage of development- the blastocyst. Because of their isolation from preimplantation embryos, and its destruction that this procedure requires, their research causes plenty of controversy given that the embryo in biological terms has the status of a living being. In response to these concerns, there have been proposed some alternative ways of isolation techniques which are still in development. Until now, most of the research is conducted in mouse and human embryonic stem cells, which differ from each other mainly in terms required for in vitro maintenance of undifferentiated state, and in some morphological characteristics. Potential application of human ES cells is creating populations of cells, tissues and organs for implantation that will revolutionize medicine by providing unlimited material for implantation fully compatible with the patient's tissue. Also, the cells can be used as an in vitro system, not only for the study of differentiation of specific cell types, but also to consider the impact of new drugs and the identification of genes as a potential therapeutic targets. However, there are many obstacles to go over and have many questions to answer before any clinical treatments can begin.

Item Type: Thesis (Bachelor's thesis)
Supervisor: Marijanović, Inga
Date: 2012
Number of Pages: 15
Subjects: NATURAL SCIENCES > Biology
Divisions: Faculty of Science > Department of Biology
Depositing User: Silvana Šehić
Date Deposited: 21 Oct 2014 11:49
Last Modified: 21 Oct 2014 11:49
URI: http://digre.pmf.unizg.hr/id/eprint/3124

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