Genetics of autoimmune diseases and hypersensitivity mechanism

Josipović, Goran (2014) Genetics of autoimmune diseases and hypersensitivity mechanism. Bachelor's thesis, Faculty of Science > Department of Biology.

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Abstract

Autoimmune diseases and hypersensitivity reactions are common disorders of the immune system. Autoimmunity is caused by immune response to self antigens with the help of autoantibodies. Hypersensitivity reactions are a broader group of disorders, characterized by strong immune responses to external antigens or autoantigens present in organism. The mechanisms of autoimmunity and hypersensitivity reactions partially overlap, although the hypersensitivity reactions include additional mechanisms that are not present in autoimmunity, therefore these two disorders should be investigated separately. Genetic background was shown to be the most critical part of development and progression of these disorders. It is needed to uncover „key genes“ that trigger these disorders with special emphasis on HLA genes.

Item Type: Thesis (Bachelor's thesis)
Supervisor: Korać, Petra
Date: 2014
Number of Pages: 11
Subjects: NATURAL SCIENCES > Biology
Divisions: Faculty of Science > Department of Biology
Depositing User: Silvana Šehić
Date Deposited: 17 Nov 2014 13:15
Last Modified: 17 Nov 2014 13:15
URI: http://digre.pmf.unizg.hr/id/eprint/3291

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