Bioinformatics methods of de novo genome assembly

Glavaš, Dunja (2014) Bioinformatics methods of de novo genome assembly. Bachelor's thesis, Faculty of Science > Department of Biology.

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Abstract

Next-generation technologies have made genome sequencing cheap and fast. Genome assemblers are programs which process output data from such experiments. When computing a complete genomic sequence from many smaller fragments, they take one of the three main approaches: greedy, OLC or de Bruijn graph. This paper describes the main points in each of the three algorithms, as well as the scaffolding process, which is the next step in genome assembly.

Item Type: Thesis (Bachelor's thesis)
Supervisor: Vlahoviček, Kristian
Date: 2014
Number of Pages: 12
Subjects: NATURAL SCIENCES > Biology
Divisions: Faculty of Science > Department of Biology
Depositing User: Silvana Šehić
Date Deposited: 18 Nov 2014 12:55
Last Modified: 18 Nov 2014 12:55
URI: http://digre.pmf.unizg.hr/id/eprint/3303

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