Organisation of microtubules and spindle pole in the cells without centosomes

Polović, Mirjana (2010) Organisation of microtubules and spindle pole in the cells without centosomes. Bachelor's thesis, Faculty of Science > Department of Biology.

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Abstract

The most improtant component of the cell, responsable for microtubule assembly is gammatubulin. Gamma-tubulin induce polimerisation of alpha and beta tubulin so as microtubule assembly. Its localized mostly on the nuclei surface, and this site is discovered as most active nucleating site of microtubules. Cortical membrane and phragmoplast are also sites of microtubule assembly. Highly dynamic assembly and dissasembly of microtubules is very important in mitosis when microtubules fast move in the cell. Proteins associated with microtubules are very important in stabilization of micortubules and for their assembly. Further researches should explain molecular function of proteins which induce polimerization of microtubules on acentrosomal poles and in mitotic spindle. Also, control points of regulation microtubule`s organization centers are still insufficient explained.

Item Type: Thesis (Bachelor's thesis)
Supervisor: Leljak Levanić, Dunja
Date: 2010
Number of Pages: 16
Subjects: NATURAL SCIENCES > Biology
Divisions: Faculty of Science > Department of Biology
Depositing User: Silvana Šehić
Date Deposited: 02 Dec 2014 12:43
Last Modified: 16 Feb 2016 14:08
URI: http://digre.pmf.unizg.hr/id/eprint/3416

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