Flavonoids and sugar disease

Janković, Iva (2009) Flavonoids and sugar disease. Bachelor's thesis, Faculty of Science > Department of Biology.

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Abstract

Diabetes mellitus is metabolic and hormonal disorder characterized by persistent hyperglycaemia, resulting either from inadequate secretion of hormon insulin, an inadequate response of taregt cells to insulin, or a combination of these factors. Insulin is secreted by the beta cells of the islands of Langerhans in the pancreas in response to increased levels of glucose in the blood. Hyperglyceamia may improve and if this level exceeds renal treshold, it passes into the urine. Also, the lack of glucose as an energy source at the cellular level means that the organism has to use its stores of fat and even muscle tissue as an alternative energy source. As a result of such degenerated metabolism, there are typical symptoms of diabetes: poyuria, thirst and loss of weight. Consequently, diabetic patients develope various diseases, such as atherosclerosis, coronary artery diseases, neuropathy, nephropathy, katarats and inflammatory diseases. In ancient times humans recognized that some plants have beneficial effects in treatment of various diseases. Plants that are most commonly used in folk medicine are fruits, vegetables, nuts, seeds, herbs, spices, green tea, red wine and citruses. It has been experimentally demonstrated that all of these plants contain lots of flavonoids, natural plant pigments that have strong antioxidant activity. Since that they act as an antioxidants, flavonoids have beneficial effect on human health, because they ensure normal progression of various enzymatic and nonenzymatic reactions at a molecular level. Exactly because of these characteristics they can be useful in preventing of many diseases. Altohugh today we know pretty much about mechanisms trough which flavonoids act on a molecular level, extensive investigations are needed how we could be sure of their positive effects on the whole organism.

Item Type: Thesis (Bachelor's thesis)
Supervisor: Oršolić, Nada
Date: 2009
Number of Pages: 19
Subjects: NATURAL SCIENCES > Biology
Divisions: Faculty of Science > Department of Biology
Depositing User: Silvana Šehić
Date Deposited: 10 Dec 2014 12:58
Last Modified: 10 Dec 2014 12:58
URI: http://digre.pmf.unizg.hr/id/eprint/3496

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