Propolis constituents and its immunoadjuvant properties

Kralj, Mateja (2009) Propolis constituents and its immunoadjuvant properties. Bachelor's thesis, Faculty of Science > Department of Biology.

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Abstract

Propolis or bee glue that bees use as a sealant for unwanted open spaces in the hive has been recognized as a healing agent since ancient times. Because of its chemical composition, that is bioactive constituents, it possesses many positive characteristics. Chemical composition of propolis varies, and mainly depends of its origin. Over 300 different constituents have been determined to this day, of which flavonoids have an important place in propolis’s healing agents research. Although the mechanism of its acting is not yet cleared, on grounds of researches conducted so far, propolis is considered a safe and efficient accomplice in immunomodulation. Its immunomodulation effect depends of its composition, method of extraction and the way of application. Immunostimulative activity of propolis can be observed through activity of macrofages and NK cells, and through the cellular and humoral responses of immune system. Also, propolis has an effect similar to immunosupresor drugs, so, in cases like auto immune diseases and organ transplant, it could be used in synergy with them or as their substitute. Many researches conducted around the world as well as clinical experiences obtained from many diseases, indicate a wide therapeutical potential of propolis. Further researches could clear the mechanisms of its doing and therefore provide a wider usage in prevention and curing diseases.

Item Type: Thesis (Bachelor's thesis)
Supervisor: Oršolić, Nada
Date: 2009
Number of Pages: 9
Subjects: NATURAL SCIENCES > Biology
Divisions: Faculty of Science > Department of Biology
Depositing User: Silvana Šehić
Date Deposited: 16 Dec 2014 13:27
Last Modified: 16 Dec 2014 13:27
URI: http://digre.pmf.unizg.hr/id/eprint/3527

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