DNA nonhomologous end-joining (NHEJ) system in prokaryotes

Bartulović, Ana (2009) DNA nonhomologous end-joining (NHEJ) system in prokaryotes. Bachelor's thesis, Faculty of Science > Department of Biology.

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Abstract

DNA repair pathways of broken DNA have been intensely studied because of their importance for organism viability and genome integrity. The most important two pathways for repairing broken DNA are homologous recombination (error free) and nonhomologous end joining (error prone). Nonhomologous pathway includes two significant factors; Ku protein and LigD ligase that form a complex with DNA double strand breaks. LigD ligase has three catalytic activities (polimerase, ligase and phosphoesterase) that participate in the repair. However, it is not completely clear if these two proteins are the only participants in this repair mechanism.

Item Type: Thesis (Bachelor's thesis)
Supervisor: Ivančić Baće, Ivana
Date: 2009
Number of Pages: 9
Subjects: NATURAL SCIENCES > Biology
Divisions: Faculty of Science > Department of Biology
Depositing User: Silvana Šehić
Date Deposited: 17 Dec 2014 10:34
Last Modified: 17 Dec 2014 10:34
URI: http://digre.pmf.unizg.hr/id/eprint/3531

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