Role of the liver in iron metabolism – histochemical iron identification

Hršak, Marija (2009) Role of the liver in iron metabolism – histochemical iron identification. Bachelor's thesis, Faculty of Science > Department of Biology.

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Abstract

Iron is necessary for the basal functioning of all mammalian cells but is particularly important in cells producing hemoglobin and myoglobin. Mammals obtain iron exclusively from the diet. Iron absorption takes place in the proximal small intestine. Liver has a large capacity to store excess iron. It also plays regulatory role in iron metabolism. Specialized macrophages remove effete red cells from circulation for iron recycling. Hepcidin is the key regulator in iron homeostasis. There are several disorders attached to defect iron metabolism, e.g. hereditary hemochromatosis, aceruloplasminemia e.t.c. There are several histochemical methods for cellular iron detection and the most common method is Perl's method.

Item Type: Thesis (Bachelor's thesis)
Supervisor: Lacković Venturin, Gordana
Date: 2009
Number of Pages: 20
Subjects: NATURAL SCIENCES > Biology
Divisions: Faculty of Science > Department of Biology
Depositing User: Silvana Šehić
Date Deposited: 22 Dec 2014 12:14
Last Modified: 16 Feb 2016 14:05
URI: http://digre.pmf.unizg.hr/id/eprint/3575

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