Incidence of diabetic ketoacidosis in patients with type 2 diabetes

Gašpar, Martina (2016) Incidence of diabetic ketoacidosis in patients with type 2 diabetes. Diploma thesis, Faculty of Science > Department of Biology.

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Abstract

Diabetic ketoacidosis is one of the most dangerous acute complications of diabetes, responsible for significant mortality if not treated properly and on time. The main features of this condition are insulin deficiency and increased levels of counter-regulatory hormones (glucagon, growth hormone, catecholamines and cortisol). Until recently it was thought that ketoacidosis is present only in type 1 diabetes, but more studies reported its presence in type 2 diabetes. Aim of this study was to establish the frequency and precipitating factors for the occurrence of diabetic ketoacidosis in patients with type 2 diabetes. The research involved searching data bases in the period from July 1st 2010 until July 1st 2015 and clinical profile of patients were analyzed. In newly diagnosed patients, concentration of blood glucose, acid-base status and the values of glycated hemoglobin were determined. Out of 72 patients, 27 (37.2%) had type 1 and 45 (62.5%) had type 2 diabetes. Among patients with type 1 diabetes, 8 (27.5%) patients had an episode of ketoacidosis as the initial case of diabetes, whereas among patients with type 2, 13 (28.8%) patients had mentioned complication as a first sign of disease. Non-compliance to treatment and infection were the most common causes of ketoacidosis.

Item Type: Thesis (Diploma thesis)
Keywords: Diabetes Mellitus, ketoacidosis, precipitating factors
Supervisor: Rahelić, Dario
Co-supervisor: Đikić, Domagoj
Date: 2016
Number of Pages: 32
Subjects: NATURAL SCIENCES > Biology
Divisions: Faculty of Science > Department of Biology
Depositing User: Silvana Šehić
Date Deposited: 25 Mar 2016 08:32
Last Modified: 25 Mar 2016 08:32
URI: http://digre.pmf.unizg.hr/id/eprint/4648

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