Blood doping

Rožmanić, Carmen (2015) Blood doping. Bachelor's thesis, Faculty of Science > Department of Biology.

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Abstract

Blood doping entails all illegal methods of increasing oxygen supply into the muscles. They include blood transfusion, use of substances that stimulate erythropoiesis or oxygen carrier substances similar to hemoglobin, natural or artificial high altitude training, and innovative gene therapy. Blood transfusion can be homologous, where the recipient receives erythrocytes isolated from a donor, or autologous, where the donor and the recipient of erythrocytes are the same person. Detection of blood doping is based on flow cytometry, ABP (Athlete Biological Passport), discovering elevated levels of polyvinyl-chloride in the urine, differences in the size and shape of erythrocytes, proteins, miRNA and expression of T lymphocytes. The goal of the World Anti-Doping Organization and the International Olympic Committee is to perfect the existing methods and develop new ones that will detect the use of blood doping in the simplest and most economical way.

Item Type: Thesis (Bachelor's thesis)
Supervisor: Tadić, Zoran
Date: 2015
Number of Pages: 16
Subjects: NATURAL SCIENCES > Biology
Divisions: Faculty of Science > Department of Biology
Depositing User: Silvana Šehić
Date Deposited: 14 Apr 2016 13:44
Last Modified: 14 Apr 2016 13:44
URI: http://digre.pmf.unizg.hr/id/eprint/4743

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