Post-transcriptional processing of tRNA-precursor molecule

Čavka, Ivana (2016) Post-transcriptional processing of tRNA-precursor molecule. Bachelor's thesis, Faculty of Science > Department of Biology.

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Abstract

Main topic of this paper is post-transcriptional processing of tRNA precursor molecule. In a cell, tRNA molecules play a very important role. Except their well-known primary role in translation, tRNA molecules are also involved in processes such as stress response and different cellular regulation pathways. In order to properly play their roles in the cell, biomolecules have to be folded correctly. tRNAs are not exceptions to this rule, since maintenance of processes that involve tRNA molecules is crucial for cell’s viability. tRNA precursor molecules differ substantially from the mature tRNAs and, in order to become functional molecules, they have to undergo post-transcriptional processing. Processing mainly involves end processing, splicing, and ribonucleotide modifications. Paper offers a short introduction to each step with best known examples from all three domains of life (Archaea, Bacteria, Eukaryota). Except for the post-transcriptional processing, some closely related topics, such as diversity of tRNA genes and tRNA subcellular trafficking in eukaryotic cells, are also discussed.

Item Type: Thesis (Bachelor's thesis)
Supervisor: Rokov Plavec, Jasmina
Date: 2016
Number of Pages: 45
Subjects: NATURAL SCIENCES > Biology
Divisions: Faculty of Science > Department of Biology
Depositing User: Grozdana Sirotic
Date Deposited: 21 Oct 2016 10:40
Last Modified: 21 Oct 2016 10:40
URI: http://digre.pmf.unizg.hr/id/eprint/5207

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