Chronic kidney failure and mammalian adaptations during hibernation

Trupinić, Monika (2016) Chronic kidney failure and mammalian adaptations during hibernation. Bachelor's thesis, Faculty of Science > Department of Biology.

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Abstract

With growing human population, we can also see growth in the number of diseases that influence the quality of life. Chronic kidney diseases are one of the most common human diseases that we can't permanently cure. Various causes may lead to chronic kidney disease but there is visible correlation with obesity which often leads to hypertension and diabetes. Kidneys, as organs who are greatly responsible for body homeostasis, are not replaceable and every malfunction is alarming. Modern medicine and therapies help to keep normal bodily functions in departments that kidneys are not capable anymore, but those treatments are often exhausting for patients and need to be repeated constantly. One possible solution in future treatments of kidney diseases can find its inspiration in nature. Hibernating animals don't eat, drink, move or urinate, and are still completely healthy without any conseqences. The most interesting animals are bears with their unique ability to recycle urea into proteins. If we can determine genes and mechanisms involved in this process, maybe we could use it in future treatments of patients whose kidneys have failed.

Item Type: Thesis (Bachelor's thesis)
Supervisor: Lisičić, Duje
Date: 2016
Number of Pages: 15
Subjects: NATURAL SCIENCES > Biology
Divisions: Faculty of Science > Department of Biology
Depositing User: Palma Dizdarevic
Date Deposited: 11 May 2017 10:30
Last Modified: 11 May 2017 10:30
URI: http://digre.pmf.unizg.hr/id/eprint/5514

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