Embryonic stem cells

Tokić, Mirta (2016) Embryonic stem cells. Bachelor's thesis, Faculty of Science > Department of Biology.

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Abstract

Embryonic stem cells (ESC) are derived from the inner cell mass (ICM) of a blastocyst. These cells have properties like self-renewal and pluripotency which makes them a popular subject of research in developmental biology but also a hope for their use in, for example, regenerative therapies and the treatment of lifestyle diseases in the near future. In order for them to be applied in therapies, the molecular background has to be well understood. As some communities disapproved of using human embryos for scientific research, scientists succeeded in obtaining pluripotent cells from mature somatic cells using only transcriptional factors where the use of external pluripotent cells was not necessary. These cells are called induced pluripotent stem cells (iPSC). The understanding of ESC and iPSC are far from complete: advanced techniques in their cultivation and manipulation will provide a better insight into the complexity of signal networks and regulation systems of these cells and thus enable their wider application.

Item Type: Thesis (Bachelor's thesis)
Supervisor: Lacković-Venturin, Gordana
Date: 2016
Number of Pages: 23
Subjects: NATURAL SCIENCES > Biology
Divisions: Faculty of Science > Department of Biology
Depositing User: Palma Dizdarevic
Date Deposited: 11 May 2017 12:11
Last Modified: 11 May 2017 12:11
URI: http://digre.pmf.unizg.hr/id/eprint/5524

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