"Black yeast" from genus Exophiala, susceptibility to antimycotics

Drčelić, Marina (2014) "Black yeast" from genus Exophiala, susceptibility to antimycotics. Diploma thesis, Faculty of Science > Department of Biology.

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Abstract

Opportunistic pathogens under the common name "black yeasts" developed ajdustments to the extreme conditions of a human habitat. One of the ecological niches where microorganisms of this group are usually found is sanitary facilities. In this thesis, "black yeast" Exophiala dermatiditis was isolated out of 28 smear test samples taken from bathroom tubs and shower cabin drains from sanitary facilities of households in Zagreb. The species was identified through protein mass spectrometry. Exophiala dermatiditis causes phaeohyphomycosis and neurotropic infections, mostly in immunocompromised individuals. By maintaining personal hygiene and habitat hygiene we can prevent infections caused by this oportunistic pathogen. Microdilution test has shown that out of all cleaning products, disinfectant and antiseptics tested, the most efficient antymicotic effect on Exophiala dermatitidis was exhibited by Plivasept Blue®. In the case when the infection manifests in an individual, treatment by antimycotics is necessary. Out of the all antimycotics tested, greatest efficiency was shown by Amphotericin B.

Item Type: Thesis (Diploma thesis)
Keywords: Exophiala dermatitidis, opportunistic pathogen, antimycotic, disinfectant, mass spectrometry, microdilution test, phaeohyphomycosis
Supervisor: Kosalec, Ivan
Co-supervisor: Oršolić, Nada
Date: 2014
Number of Pages: 54
Subjects: NATURAL SCIENCES > Biology
Divisions: Faculty of Science > Department of Biology
Depositing User: Grozdana Sirotic
Date Deposited: 25 Mar 2014 13:46
Last Modified: 23 Sep 2014 08:48
URI: http://digre.pmf.unizg.hr/id/eprint/709

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